Avatar Cells: How To Construct "Designed Cell-Cell Communications"
Description:
Cell-cell communication is fundamental to biological systems. By designing and utilizing its functions, it becomes possible not only to simulate but also to enhance the body's innate functions, such as immune capability, regenerative ability, metabolic regulation, and hormonal balance. This groundbreaking innovation in design and utilization holds the key to maintaining optimal health and unlocking new frontiers in biomedical science, paving the way for the development of micro/nano-scale living robots.
This workshop will introduce the "Intracellular CA (cybernetic avatar)" project, led by Japan's Cabinet Office, which aims to develop "Avatar cells"-an innovative approach integrating advanced biological functions within rapidly evolving micro/nano-technologies. From molecular interactions at the nanoscale to multicellular system applications, the discussion will take a multidimensional approach to exploring these technologies and their potential in advancing biological functions. Through the perspective of "Designed cell-cell communication," this project seeks to co-create new biological architectures, pioneering research at the cutting edge.
Specifically, the workshop will cover "triggered bio-functions", "in-vivo acquisition of micro/nano-scale living robots", "information transmission from body to world", as well as the development of "human-in-the-loop evaluation and control frameworks".
Objectives:
For those interested in Learning, International collaboration works, Technology transfer, Commercialization, Organizing business consortium about technologies related to designed cell-cell communication, including Avatar cells, Designer cells, Lipid nanoparticle applications, On-chip cell manipulation and analysis, AI-based analysis, Organ-on-chip technology, and Applications for tumor cells and senescent cells. For those interested in the Moonshot Project (Intracellular CA) led by Japan's Cabinet Office.
Presentation Titles:
- Yoko Yamanishi - Avatar cells: How to construct “designed cell-cell communications"
- Niko Kimura - Lipid-based nanoparticles: on-chip production and applications for extended functionalization of cells
- Kosuke Dodo - Chemically induced protein dimerization: A key switch for controlling avatar cells
- Shigeo S. Sugano - Programming cells with orthogonal genes: CRISPR-Cas and plant-hormone-based switches
- Shinya Sakuma - On-chip robotic flow control: Exploring frontiers of single-cell manipulation and analysis
- Yoshitaka Shirasaki - Visualization and isolation technologies for cell-cell communications
- Takashi Kamatani - From visualization to insight: Image feature extraction and statistical modeling of on-chip cell–cell communication
- Takeshi Hayakawa - Microphysiological system for the evaluation of avatar cells